Neurophysics Research

(Turn and face the strange*)

Active sensing:

This program addresses how orofacial motor actions that underlie exploration, with current emphasis on the lingual, nasal, and vibrissa sensorimotor systems, encode a stable world view through the coordinated movement of sensory organs and sensors. It includes anatomical, behavioral, and electrophysiological components.

Microcirculation within the brain:

This program explores the structure and, vasodyanmic, and neurodynamic control of blood flow in the brain. This program includes anatomical, computational, and opto- and electrophysiological components. We further study the consequences of interruptions to cortical blood flow at the level of individual microvessels as a means to understand the neuroimflammation and nmicrostrokes.


This program creates new tools for our scientific studies. We currently focus on: (1) imaging of cortical axons and spines deep within brain tissue through the use of adaptive optics with two-photon microscopy; (2) construction of an active digital atlas of the mouse brain, with current emphasis on the brainstem; and (3) volition control of neuromodulation in the brains of behaving animals using nanoMolar affinity cell-based molecular sensors. This program has strong imaging and computational components.

Neurophysics-Feb-2020 missing Celine

*David Bowie, 1947-2016